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Xanthelasma palpebrarum

Xanthelasma palpebrarum is the most common cutaneous xanthoma, characterized by yellowish plaques over eyelids – most commonly, over the inner canthus of the upper lid. It is triggered by hyperlipidemia, thyroid dysfunction, and diabetes mellitus. Xanthelasma results from perivascular infiltration of mono- and multinucleated foam cells within lipid-laden cytoplasmic vacuoles in the superficial reticular dermis. Different modalities of treatment, such as simple surgical excision, cryotherapy, chemical peeling with trichloroacetic acid, radiofrequency, and laser, are used in the treatment of xanthelasma palpebrarum. A brief review of current treatment strategies is presented here.

Who gets Xanthelasma Palpebrarum?

  • Xanthelasma Palpebrarum is usually observed in middle-aged and older adults. A few cases have been occasionally reported in children and teenagers
  • Both males and females may be affected; a female predominance is noted
  • Individuals of all racial and ethnic background may be affected. Worldwide, no geographical localization has been reported

What are the Causes of Xanthelasma Palpebrarum?

The exact cause of development of Xanthelasma Palpebrarum is not well-established. In about half the cases, increased levels of lipid or LDL/VLDL cholesterol in the blood are noted

When the metabolism of fat/lipid is affected, lipids in blood combine with certain proteins to form water-insoluble lipoproteins, which accumulate beneath the skin to form xanthomas

What are the Signs and Symptoms of Xanthelasma Palpebrarum?

  • Presence of small, well-defined, flat skin lesions in the form of papules and plaques
  • Several lesions may form around the eye, on the upper and lower eyelids; generally, the upper eyelids are affected
  • The lesions may have yellowish discoloration
  • They are usually painless; some are tender to touch
  • When these increase in size, they are denoted as xanthomas. Some may grow large over many months, to form tumors
  • In some individuals, the lesions are observed to form symmetrically around the eyes

What are the Risk Factors ?

  • Metabolic or genetic conditions causing elevated fat levels in blood (hyperlipidemia) or increased blood cholesterol levels (hypercholesterolemia): It is reported that about 50% of the individuals with Xanthelasma Palpebrarum have abnormal levels of fat/cholesterol in blood
  • Use of certain medications
  • Poorly-controlled diabetes
  • Hypothyroidism or thyroid dysfunction
  • High-fat diet and lack of physical activities/exercise
  • High BMI levels: Obesity or overweight conditions
  • Excess consumption of alcohol

Although these area unit terribly visual skin lesions, luckily they’re strictly cosmetic and superficial and that they don’t grow too deeply into the corium. The fat accountable resides between the superficial a part of the corium and also the stratum. Therefore, made treatment and removal, while not going away scarring, is definitely possible. varied management techniques area unit examined starting from using Garlic, Castor oil, all the thanks to TCA, Surgery and Removal creams

Even though these deposits themselves won’t hurt you, they’ll be a proof that you simply have dangerously high sterol levels and will be at the next risk for heart disease. it’s continually an honest plan to be verified by your Dr.. For additional details regarding the doable health indicators that this skin condition are often Associate in Nursing indicator to, move to Understanding xanthoma Causes.

Is it Harmful ?

Although these area unit terribly visual skin lesions, luckily they’re strictly cosmetic and superficial and that they don’t grow too deeply into the corium. The fat accountable resides between the superficial a part of the corium and also the stratum. Therefore, made treatment and removal, while not going away scarring, is definitely possible. varied management techniques area unit examined starting from using Garlic, Castor oil, all the thanks to TCA, Surgery and Removal creams

Even though these deposits themselves won’t hurt you, they’ll be a proof that you simply have dangerously high sterol levels and will be at the next risk for heart disease. it’s continually an honest plan to be verified by your Dr.. For additional details regarding the doable health indicators that this skin condition are often Associate in Nursing indicator to, move to Understanding xanthoma Causes.

In Medical term

A high cholesterol level will cause xanthoma however it may also be found in patients with traditional or low-level cholesterol. the most frequent queries that sufferers of this condition raise are what causes Xanthelasma?

There are smart and dangerous cholesterol. while smart cholesterol is understood as alpha-lipoprotein (high-density lipoprotein) dangerous cholesterol is understood as low-density lipoprotein (low-density lipoprotein) low levels within the alpha-lipoprotein in addition as a high level within the low-density lipoprotein is a trigger of xanthoma. disease and hypercholesterolemia are popularly called transmitted high cholesterol are the opposite causes of xanthoma. This condition can possibly not cause any variety of physical distress. Loss of vision is usually not thought-about an element once the question of removal comes up.

Eyelid bumps square measure red lumps showing on the eyelids wherever the lash meets the lid. they're usually harmful and don't need any medical treatment as they will go away with a home remedy or naturally with time.
March 6, 2019 Read more